Is the white blood cell count in PRP the cause of pain after knee joint injection of PRP

1. Does High White Blood Cell (WBC) Count in PRP Cause Knee Pain?

While some believe WBCs may trigger inflammation, studies show that improper injection technique is the leading cause of post-PRP knee pain, not the PRP itself.

2. What Causes Swelling After PRP Injections?

• Poor Sterilization (infection risk)
• Synovial Membrane Irritation (highly sensitive tissue)
• Excess Joint Fluid (should be drained before PRP)
• Unskilled Injection (repeated punctures cause trauma)

3. How Can Doctors Minimize PRP Injection Risks?

✅ Use ultrasound guidance for precision
✅ Avoid synovial membrane injections
✅ Drain joint effusion first
✅ Follow strict sterile protocols

4. Is PRP Safe for Joint and Aesthetic Treatments?

Yes—when performed correctly, PRP has a low complication rate and is widely used in:

• Orthopedics (knee osteoarthritis, tendon injuries)
• Dermatology (skin rejuvenation, hair loss)
• Dentistry (bone grafting, gum regeneration)

5. Can PRP Itself Cause Swelling?

No—most swelling is due to poor technique, not PRP composition. Ultrasound-guided injections minimize risks.